What is a critical consideration for a nurse during the first 15 minutes of a blood transfusion?

During the first 15 minutes of a blood transfusion, assessing for transfusion reactions is crucial. This initial period is significant because most transfusion reactions manifest within the first few minutes of administration. Nurses are trained to observe for signs such as fever, chills, rash, or difficulty breathing. Early detection of a reaction can be life-saving and may prevent serious complications. The patient’s condition and response to the transfusion need to be closely monitored to ensure safety and intervene promptly if any adverse effects occur. This critical vigilance aligns with established safety protocols for transfusion therapy.